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Ellagic Acid - Medical References


Dr. Daniel Nixon
Medical University of South Carolina (MUSC)


Dr. Nixon began studying Ellagic Acid in 1993, recently published results:

Cervical Cancer Cells - HPV (Human Papilloma Virus) exposed to Ellagic Acid from Red Raspberries experienced apoptosis (normal cell death).

The tests reveal similar results for breast, pancreas, esophageal, skin, colon, and prostate cancer cells. In addition, positive responses are observed in: periodontal disease, radiation induced chromosomal damage, slowing the degenerative process of aging, neurodegenerative diseases, diabetic retinopathy.

Other References

There is clinical evidence that Ellagic acid may inhibit tumors of the prostate and cervix. Preliminary studies in volunteers indicate Ellagic acid shows up in cervical tissue after oral ingestion of red raspberries. One study will evaluate women with atypical squamous cells of undetermined significance (ASCUS) in which there is neither treatment nor clinical evaluation available. ASCUS represents as much as 10% of all Papanicolaou smears in the US and represents approximately 5 million females. In this population, women infected with human papillomaviruses (HPV) types 16 and/or 18 are at the greatest risk of developing cervical cancer at some stage in their lives. This population represents approximately one million women in the United States alone, and in India is one of the two major cancers affecting women.

Researchers at the National Center for Health Statistics (NCHS) in Hyattsville, Maryland established a connection between reduced risk of heart attack and increased intake of salicylates. They found that during a 10 year period beginning in 1960, when heart attack rates began to decline, non-aspirin salicylate consumption went up due to salicylate in processed foods which used a synthetic version to add flavor and aroma.

Ellagitannins are also believed by herbalists to be effective in treating diarrhoea, nausea, vomiting and morning sickness in pregnancy. Herbalists do not, however, recommend you use red raspberry for this purpose at home even though red raspberry leaves are included in several herbal pregnancy formulas sold in the United States for women with a history of miscarriage or difficult pregnancy for the purpose of regulating uterine contractions, morning sickness, hot flashes, diarrhoea (use weak tea for infants), and for reducing excessive menstrual flow. The herb is also used as a gargle for sore throats.

Ellagic - Detailed graph points of intervention

Ellagic -  Metabolic pathways of Ellagitannins

Ellagic Acid - Background

Ellagic Acid - History

Ellagic Acid - Evidence

Ellagic Acid - Clinical Studies

Ellagic Acid - Mode of Action

Ellagic Acid - Medical References

Ellagic Acid - Med. References cont.

Ellagic Acid - Reference Papers

General Health - Resources

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