Ellagic Acid - Clinical Studies
The Hollings Clinic has identified the Meeker Red Raspberry for their studies.
Our product is only made from Meeker's red raspberry seed flour.
Other Studies come from: College of Medicine, University of Illinois Northwestern University School of Medicine Department of Preventive Medicine, Ohio State University.
Research on ellagic acid shows the following effects:
1. Reduces the risk of esophageal cancer by collecting in the epithelial cells in the digestive tract
2. Reduces the development of esophageal cancer 3. Decreases lipid peroxidation
4. Is an effective free radical scavenger
5. Reduces tumor incidence and development
6. Protects from radiation-induced chromosome damage
7. Prevents liver cancer
8. Prevents lung cancer
9. Prevents skin cancer
10. Prevents embryo mutation and carcinogenesis in animal models given toxins
11. Works synergistically with quercetin as an anticarcinogenic
Ellagic Acid - Mode of Action
Ellagic Acid itself is not naturally present in plants. However, polymers of Gallic acid and hexahydroxydipenoyl (HHDP) are linked to glucose centers to form compounds known as ellagitannins.
When two Gallic acid groups are linked side by side within a tannin molecule an HHDP group is formed. Ellagic Acid is the result when the HHDP group is cleaved from the tannin molecule and
spontaneously rearranges.
It is the ellagitannins that are present in red raspberries.
The Meeker Red Raspberry contains the most ellagitannins and is thus the best source of Ellagic Acid.
Other foods such as strawberries, pomegranates, and walnuts contain much less amounts of Ellagitannins. The bioavailability from these other sources has not been confirmed.
Ellagic acid is a scavenger of cancer-causing chemicals, making them inactive, inhibiting the ability of other chemicals to cause mutations in bacteria. Additionally, Ellagic Acid from red
raspberries prevents binding of carcinogens to DNA, and reduces the incidence of cancer in cultured human cells exposed to carcinogens. |
